山东师范大学学报(自然科学版)

2019, v.34;No.148(04) 478-489

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气质类型对抑郁症影响的神经基础
THE NEURAL BASIS OF PERSONALITY STYLES EFFECT ON DEPRESSION

刘惠娟;邱江;
Liu Huijuan;Qiu Jiang;Chongqing Youth Vocational Technical College;Southwest University;

摘要(Abstract):

采用FMRI技术研究抑郁组和控制组的脑区差异,并对研究结果的左侧顶上小叶、左侧梭状回、左侧颞上回、左侧额下回、右侧中央前回以及左侧中部扣带六个差异脑区的灰质体积进行方差分析,发现不同气质类型的抑郁组和控制组被试这六个脑区的灰质体积均存在不同程度的差异.这些研究结果可能为个体由消极的人格特质发展为抑郁症提供生物基础,也为个体心理健康的预测和早期心理风险评估提供潜在的生物学标记.
In this study, our objective was to explor the behavioral differences between the depressive patients with the control group. There are 99 patients with moderate to severe depression and 97 normal persons whose gender, age, education level matched as control group subjects. Two sample t-test analysis was performed to investigate the difference in the brain gray matter volume(GMV) between the depression group and control group. Compared with control group, the depression group displayed lower gray volume in the left superior parietal, the left fusiform, the left superior temporal gyrus, the left inferior frontal gyrus, the right precentral and the left cingulate.Overall, our findings provide a new direction for the research and evidence theory of personality,and also provides a physical basis for the negative personality styles grow into depression. These findings indicat that personality styles that consider person-centered traits may be more important and effective to predict individuals mental health, and these results would provide a potential brain biomarker for early individual psychological risk assessments.

关键词(KeyWords): 气质类型;抑郁症;个体差异;灰质体积
personality styles;depression;individual difference;gray matter volume

Abstract:

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基金项目(Foundation): 国家自然科学基金资助项目(31771231,31571137)

作者(Author): 刘惠娟;邱江;
Liu Huijuan;Qiu Jiang;Chongqing Youth Vocational Technical College;Southwest University;

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